Desmoglein 2 anticorps (CF®568)

N° du produit ABIN6162207

Cet anticorps Souris Monoclonal détecte spécifiquement Desmoglein 2 dans WB, IF et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour Desmoglein 2 anticorps (CF®568) (ABIN6162207)

Antigène: Desmoglein 2 (DSG2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 2 est conjugé à/à la CF®568

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 6D8

Détail du produit anti-Desmoglein 2 anticorps (CF®568)

Fonction: Mouse Monoclonal anti-Desmoglein-2 (6D8), CF568 Conjugate

Attributs du produit: This antibody recognizes the extracellular domain of human desmoglein-2 (DSG2), a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cytoplasmic region containing five desmoglein repeat domains which share homology with the cadherin repeats. Desmoglein-2 has been shown to be important in establishing cell-cell adhesion and function in epithelial cells. It was originally identified in colon carcinoma and colon, and was named HDGC (human desmoglein colon). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human full-length DSG2 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

A431, HepG2 or K562 cells. Heart or Colon

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Desmoglein 2

Antigène: Desmoglein 2 (DSG2)

Autre désignation: Desmoglein-2

Sujet: ARVC10, ARVD10, Cadherin family member 5, CDHF5, CMD1BB, Desmoglein-2, DSG2, HDGC, Human Desmoglein Colon

Poids moléculaire: ~165 kDa

ID gène: 1829, 412597

UniProt: Q14126

Pathways: Cell-Cell Junction Organization